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Allelic variance between GRM6 mutants, Grm6(nob3) and Grm6(nob4) results in differences in retinal ganglion cell visual responses

An electroretinogram (ERG) screen identified a mouse with a normal a-wave but lacking a b-wave, and as such it was designated no b-wave3 (nob3). The nob3 phenotype mapped to chromosome 11 in a region containing the metabotropic glutamate receptor 6 gene (Grm6). Sequence analyses of cDNA identified a...

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Bibliografiska uppgifter
Huvudupphovsmän: Maddox, Dennis M, Vessey, Kirstan A, Yarbrough, Gary L, Invergo, Brandon M, Cantrell, Donald R, Inayat, Samsoon, Balannik, Victoria, Hicks, Wanda L, Hawes, Norman L, Byers, Shannon, Smith, Richard S, Hurd, Ron, Howell, Douglas, Gregg, Ronald G., Chang, Bo, Naggert, Jürgen K, Troy, John B, Pinto, Lawrence H, Nishina, Patsy M, McCall, Maureen A
Materialtyp: Artigo
Språk:Inglês
Publicerad: Blackwell Science Inc 2008
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC2614010/
https://ncbi.nlm.nih.gov/pubmed/18687716
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2008.157289
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