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New mouse models for recessive retinitis pigmentosa caused by mutations in the Pde6a gene
The heterotetrameric phosphodiesterase (PDE) 6 complex, made up of α, β and two γ subunits, regulates intracellular cGMP levels by hydrolyzing cGMP in response to light activation of G protein coupled receptors in cones and rods, making it an essential component of the visual phototransduction casca...
Gorde:
| Egile Nagusiak: | , , , , |
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| Formatua: | Artigo |
| Hizkuntza: | Inglês |
| Argitaratua: |
Oxford University Press
2009
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| Gaiak: | |
| Sarrera elektronikoa: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2644649/ https://ncbi.nlm.nih.gov/pubmed/18849587 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddn327 |
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