INHIBITION OF NEUROBLASTOMA XENOGRAFT GROWTH BY HSP90 INHIBITOR

BACKGROUND: Advanced-stage neuroblastomas are often resistant to chemotherapy. Heat shock protein (Hsp) 90 is a molecular chaperone that maintains the stability of important signal transduction proteins. We have previously reported that geldanamycin (GA), Hsp90 inhibitor, decreases Raf-1 and Akt pro...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Hauptverfasser: Kang, Junghee, Kamal, Adeela, Burrows, Francis J., Evers, B. Mark, Chung, Dai H.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2006
Schlagworte:
Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2613690/
https://ncbi.nlm.nih.gov/pubmed/16827123
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!

Ähnliche Einträge