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INHIBITION OF NEUROBLASTOMA XENOGRAFT GROWTH BY HSP90 INHIBITOR

BACKGROUND: Advanced-stage neuroblastomas are often resistant to chemotherapy. Heat shock protein (Hsp) 90 is a molecular chaperone that maintains the stability of important signal transduction proteins. We have previously reported that geldanamycin (GA), Hsp90 inhibitor, decreases Raf-1 and Akt pro...

Täydet tiedot

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Bibliografiset tiedot
Päätekijät: Kang, Junghee, Kamal, Adeela, Burrows, Francis J., Evers, B. Mark, Chung, Dai H.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2006
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC2613690/
https://ncbi.nlm.nih.gov/pubmed/16827123
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