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Proper Restoration of Excitation-Contraction Coupling in the Dihydropyridine Receptor β(1)-null Zebrafish Relaxed Is an Exclusive Function of the β(1a) Subunit
The paralyzed zebrafish strain relaxed carries a null mutation for the skeletal muscle dihydropyridine receptor (DHPR) β(1a) subunit. Lack of β(1a) results in (i) reduced membrane expression of the pore forming DHPR α(1S) subunit, (ii) elimination of α(1S) charge movement, and (iii) impediment of ar...
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| Autors principals: | , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
American Society for Biochemistry and Molecular Biology
2009
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2613631/ https://ncbi.nlm.nih.gov/pubmed/19008220 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M807767200 |
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