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Domain cooperativity in the β(1a) subunit is essential for dihydropyridine receptor voltage sensing in skeletal muscle

The dihydropyridine receptor (DHPR) β(1a) subunit is crucial for enhancement of DHPR triad expression, assembly of DHPRs in tetrads, and elicitation of DHPRα(1S) charge movement—the three prerequisites of skeletal muscle excitation–contraction coupling. Despite the ability to fully target α(1S) into...

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Autori principali: Dayal, Anamika, Bhat, Vinayakumar, Franzini-Armstrong, Clara, Grabner, Manfred
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 2013
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3645543/
https://ncbi.nlm.nih.gov/pubmed/23589859
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1301087110
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