Differential Interactions of Thrombospondin-1, -2, and -4 with CD47 and Effects on cGMP Signaling and Ischemic Injury Responses

Thrombospondin-1 regulates nitric oxide (NO) signaling in vascular cells via CD47. Because CD47 binding motifs are conserved in the C-terminal signature domains of all five thrombospondins and indirect evidence has implied CD47 interactions with other family members, we compared activities of recomb...

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Main Authors: Isenberg, Jeff S., Annis, Douglas S., Pendrak, Michael L., Ptaszynska, Malgorzata, Frazier, William A., Mosher, Deane F., Roberts, David D.
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Biochemistry and Molecular Biology 2009
Assuntos:
Mechanisms of Signal Transduction
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2613617/
https://ncbi.nlm.nih.gov/pubmed/19004835
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M804860200
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