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Thrombospondin-1-CD47 blockade and exogenous nitrite enhance ischemic tissue survival, blood flow and angiogenesis via coupled NO-cGMP pathway activation
Tissue ischemia and ischemia-reperfusion (I/R) remain sources of cell and tissue death. Inability to restore blood flow and limit reperfusion injury represents a challenge in surgical tissue repair and transplantation. A central regulator of blood flow, reperfusion signaling and angiogenesis is nitr...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2768066/ https://ncbi.nlm.nih.gov/pubmed/19481167 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.niox.2009.05.005 |
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