Cargando...

Neprilysin gene expression requires binding of the amyloid precursor protein intracellular domain to its promoter: implications for Alzheimer disease

Amyloid β-peptide (Aβ) accumulation leads to neurodegeneration and Alzheimer disease; however, amyloid metabolism is a dynamic process and enzymic mechanisms exist for Aβ removal. Considerable controversy surrounds whether the intracellular domain of the amyloid precursor protein (AICD) regulates ex...

Descrición completa

Gardado en:
Detalles Bibliográficos
Main Authors: Belyaev, Nikolai D, Nalivaeva, Natalia N, Makova, Natalia Z, Turner, Anthony J
Formato: Artigo
Idioma:Inglês
Publicado: Nature Publishing Group 2009
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2613207/
https://ncbi.nlm.nih.gov/pubmed/19057576
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/embor.2008.222
Tags: Engadir etiqueta
Sen Etiquetas, Sexa o primeiro en etiquetar este rexistro!