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Endoplasmic Reticulum Stress, PrP Trafficking, and Neurodegeneration
In this issue of Developmental Cell, Rane et al. report a cellular pathway to link PrP(Sc), via ER stress and the activation of a preemptive quality control process, to neurodegeneration in a PrP-dependent manner. This pathway puts together several pieces in the puzzle of the relationship between Pr...
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
2008
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| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2613161/ https://ncbi.nlm.nih.gov/pubmed/18804431 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.devcel.2008.09.001 |
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