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The Neurosteroid Environment in the Hippocampus Exerts Bi-Directional Effects on Seizure Susceptibility in Mice
The progesterone derivative allopregnanolone (ALLO) rapidly potentiates γ-aminobutyric acid(A) (GABA(A)) receptor mediated inhibition. The present studies determined whether specific manipulation of neurosteroid levels in the hippocampus would alter seizure susceptibility in an animal model genetica...
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Main Authors: | , , , , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
2008
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2613069/ https://ncbi.nlm.nih.gov/pubmed/18840414 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.brainres.2008.09.042 |
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