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Local Changes in Neurosteroid Levels in the Substantia Nigra Reticulata and the Ventral Tegmental Area Alter Chronic Ethanol Withdrawal Severity in Male Withdrawal Seizure-Prone Mice
BACKGROUND: Allopregnanolone (ALLO) is a potent positive modulator of γ-aminobutyric acid(A) receptors (GABA(A)Rs) that affects ethanol withdrawal. Finasteride (FIN), a 5α-reductase inhibitor that blocks the formation of ALLO and other GABAergic neurosteroids, alters ethanol sensitivity. Recently, w...
Gorde:
| Egile Nagusiak: | , , , , , , , |
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| Formatua: | Artigo |
| Hizkuntza: | Inglês |
| Argitaratua: |
2012
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| Gaiak: | |
| Sarrera elektronikoa: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3620817/ https://ncbi.nlm.nih.gov/pubmed/23278716 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/acer.12027 |
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