Decreased Anticonvulsant Efficacy of Allopregnanolone During Ethanol Withdrawal in Female Withdrawal Seizure-Prone vs. Withdrawal Seizure-Resistant Mice

The GABAergic neurosteroid allopregnanolone (ALLO) has been repeatedly shown to have an increased anticonvulsant effect during ethanol withdrawal in rats and in C57BL/6J mice. In contrast, the seizure prone DBA/2J inbred strain and the Withdrawal Seizure-Prone (WSP) selected line exhibited decreased...

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מידע ביבליוגרפי
Main Authors: Beckley, Ethan H., Fretwell, Andrea M., Tanchuck, Michelle A., Gililland, Katherine R., Crabbe, John C., Finn, Deborah A.
פורמט: Artigo
שפה:Inglês
יצא לאור: 2007
נושאים:
Article
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC2262286/
https://ncbi.nlm.nih.gov/pubmed/18045626
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuropharm.2007.10.006
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