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Differing patterns of genetic instability in mice deficient in the mismatch repair genes Pms2, Mlh1, Msh2, Msh3 and Msh6

Defects in genes associated with DNA mismatch repair (MMR) have been linked to hereditary colon cancer. Because the MMR pathway includes multiple factors with both overlapping and divergent functions, we sought to compare the impact of deficiencies in each of several MMR genes on genetic instability...

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שמור ב:
מידע ביבליוגרפי
Main Authors: Hegan, Denise Campisi, Narayanan, Latha, Jirik, Frank R., Edelmann, Winfried, Liskay, R. Michael, Glazer, Peter M.
פורמט: Artigo
שפה:Inglês
יצא לאור: 2006
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC2612936/
https://ncbi.nlm.nih.gov/pubmed/16728433
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/carcin/bgl079
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