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Differing patterns of genetic instability in mice deficient in the mismatch repair genes Pms2, Mlh1, Msh2, Msh3 and Msh6

Defects in genes associated with DNA mismatch repair (MMR) have been linked to hereditary colon cancer. Because the MMR pathway includes multiple factors with both overlapping and divergent functions, we sought to compare the impact of deficiencies in each of several MMR genes on genetic instability...

詳細記述

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書誌詳細
主要な著者: Hegan, Denise Campisi, Narayanan, Latha, Jirik, Frank R., Edelmann, Winfried, Liskay, R. Michael, Glazer, Peter M.
フォーマット: Artigo
言語:Inglês
出版事項: 2006
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC2612936/
https://ncbi.nlm.nih.gov/pubmed/16728433
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/carcin/bgl079
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