PCNA and Msh2-Msh6 Activate an Mlh1-Pms1 Endonuclease Pathway Required for Exo1-independent Mismatch Repair

Genetic evidence has implicated multiple pathways in eukaryotic DNA mismatch repair (MMR) downstream of mispair recognition and Mlh1-Pms1 recruitment, including Exonuclease 1 (Exo1) dependent and independent pathways. We identified 14 mutations in POL30, which encodes PCNA in Saccharomyces cerevisia...

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Detalhes bibliográficos
Main Authors: Goellner, Eva M., Smith, Catherine E., Campbell, Christopher S., Hombauer, Hans, Desai, Arshad, Putnam, Christopher D., Kolodner, Richard D.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4113420/
https://ncbi.nlm.nih.gov/pubmed/24981171
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2014.04.034
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