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Elevated levels of mutation in multiple tissues of mice deficient in the DNA mismatch repair gene Pms2
The Pms2 gene has been implicated in hereditary colon cancer and is one of several mammalian homologs of the Escherichia coli mutL DNA mismatch repair gene. To determine the effect of Pms2 inactivation on genomic integrity in vivo, hybrid transgenic mice were constructed that carry targeted disrupti...
में बचाया:
| मुख्य लेखकों: | , , , , |
|---|---|
| स्वरूप: | Artigo |
| भाषा: | Inglês |
| प्रकाशित: |
The National Academy of Sciences of the USA
1997
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| विषय: | |
| ऑनलाइन पहुंच: | https://ncbi.nlm.nih.gov/pmc/articles/PMC20332/ https://ncbi.nlm.nih.gov/pubmed/9096356 |
| टैग : |
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