Protein Kinase Cζ Represses the Interleukin-6 Promoter and Impairs Tumorigenesis In Vivo

Gene alterations in tumor cells that confer the ability to grow under nutrient- and mitogen-deficient conditions constitute a competitive advantage that leads to more-aggressive forms of cancer. The atypical protein kinase C (PKC) isoform, PKCζ, has been shown to interact with the signaling adapter...

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Main Authors: Galvez, Anita S., Duran, Angeles, Linares, Juan F., Pathrose, Peterson, Castilla, Elias A., Abu-Baker, Shadi, Leitges, Michael, Diaz-Meco, Maria T., Moscat, Jorge
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2009
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2612492/
https://ncbi.nlm.nih.gov/pubmed/18955501
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.01294-08
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