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Inactivation of Rho GTPases by Statins Attenuates Anthrax Lethal Toxin Activity
Anthrax lethal factor (LF), secreted by Bacillus anthracis, interacts with protective antigen to form a bipartite toxin (lethal toxin [LT]) that exerts pleiotropic biological effects resulting in subversion of the innate immune response. Although the mitogen-activated protein kinase kinases (MKKs) a...
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| Autori principali: | , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
American Society for Microbiology (ASM)
2009
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2612271/ https://ncbi.nlm.nih.gov/pubmed/18936176 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.01005-08 |
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