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Upregulation of the Host SLC11A1 Gene by Clostridium difficile Toxin B Facilitates Glucosylation of Rho GTPases and Enhances Toxin Lethality
Pseudomembranous enterocolitis associated with Clostridium difficile infection is an important cause of morbidity and mortality in patients being treated with antibiotics. Two closely related large protein toxins produced by C. difficile, TcdA and TcdB, which act identically but at different efficie...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Microbiology
2013
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3719560/ https://ncbi.nlm.nih.gov/pubmed/23690404 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.01177-12 |
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