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mtDNA depletion confers specific gene expression profiles in human cells grown in culture and in xenograft
BACKGROUND: Interactions between the gene products encoded by the mitochondrial and nuclear genomes play critical roles in eukaryotic cellular function. However, the effects mitochondrial DNA (mtDNA) levels have on the nuclear transcriptome have not been defined under physiological conditions. In or...
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Main Authors: | , , , , , , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
BioMed Central
2008
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2612029/ https://ncbi.nlm.nih.gov/pubmed/18980691 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2164-9-521 |
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