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Generation of Rho Zero Cells: Visualization and Quantification of the mtDNA Depletion Process
Human mitochondrial DNA (mtDNA) is located in discrete DNA-protein complexes, so called nucleoids. These structures can be easily visualized in living cells by utilizing the fluorescent stain PicoGreen(®). In contrary, cells devoid of endogenous mitochondrial genomes (ρ(0) cells) display no mitochon...
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| Publicado no: | Int J Mol Sci |
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| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
MDPI
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4463621/ https://ncbi.nlm.nih.gov/pubmed/25941929 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms16059850 |
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