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Generation of Rho Zero Cells: Visualization and Quantification of the mtDNA Depletion Process
Human mitochondrial DNA (mtDNA) is located in discrete DNA-protein complexes, so called nucleoids. These structures can be easily visualized in living cells by utilizing the fluorescent stain PicoGreen(®). In contrary, cells devoid of endogenous mitochondrial genomes (ρ(0) cells) display no mitochon...
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| Опубликовано в: : | Int J Mol Sci |
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| Главные авторы: | , , , , , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
MDPI
2015
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4463621/ https://ncbi.nlm.nih.gov/pubmed/25941929 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms16059850 |
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