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Generation of Rho Zero Cells: Visualization and Quantification of the mtDNA Depletion Process

Human mitochondrial DNA (mtDNA) is located in discrete DNA-protein complexes, so called nucleoids. These structures can be easily visualized in living cells by utilizing the fluorescent stain PicoGreen(®). In contrary, cells devoid of endogenous mitochondrial genomes (ρ(0) cells) display no mitochon...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Int J Mol Sci
Egile Nagusiak: Schubert, Susanna, Heller, Sandra, Löffler, Birgit, Schäfer, Ingo, Seibel, Martina, Villani, Gaetano, Seibel, Peter
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: MDPI 2015
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4463621/
https://ncbi.nlm.nih.gov/pubmed/25941929
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms16059850
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