Synthesis and Anticancer Properties of Water-Soluble Zinc Ionophores

Several water-solubilized versions of the zinc ionophore 1-hydroxypyridine-2-thione (ZnHPT), synthesized as part of the present study, have been found both to increase the intracellular concentrations of free zinc and to produce an antiproliferative activity in exponential phase A549 human lung canc...

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Detalhes bibliográficos
Main Authors: Magda, Darren, Lecane, Philip, Wang, Zhong, Hu, Weilin, Thiemann, Patricia, Ma, Xuan, Dranchak, Patricia K., Wang, Xiaoming, Lynch, Vincent, Wei, Wenhao, Csokai, Viktor, Hacia, Joseph G., Sessler, Jonathan L.
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3033660/
https://ncbi.nlm.nih.gov/pubmed/18593933
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-08-0601
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