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Solvent Structure and Hammerhead Ribozyme Catalysis
Although the hammerhead ribozyme is regarded as a prototype for understanding RNA catalysis, the mechanistic roles of associated metal ions and water molecules in the cleavage reaction remain controversial. We have investigated the catalytic potential of observed divalent metal ions and water molecu...
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| Huvudupphovsmän: | , , , |
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| Materialtyp: | Artigo |
| Språk: | Inglês |
| Publicerad: |
2008
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| Ämnen: | |
| Länkar: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2610685/ https://ncbi.nlm.nih.gov/pubmed/18420140 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.chembiol.2008.03.010 |
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