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Human hyperimmune globulin protects against the cytotoxic action of staphylococcal alpha-toxin in vitro and in vivo.

Alpha-toxin, the major cytolysin of Staphylococcus aureus, preferentially attacks human platelets and cultured monocytes, thereby promoting coagulation and the release of interleukin-1 and tumor necrosis factor. Titers of naturally occurring antibodies in human blood are not high enough to substanti...

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Autors principals: Bhakdi, S, Mannhardt, U, Muhly, M, Hugo, F, Ronneberger, H, Hungerer, K D
Format: Artigo
Idioma:Inglês
Publicat: 1989
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC260792/
https://ncbi.nlm.nih.gov/pubmed/2777380
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