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Effects of Escherichia coli hemolysin on human monocytes. Cytocidal action and stimulation of interleukin 1 release.

This study reports on the potent cytocidal and interleukin-1 releasing properties of Escherichia coli hemolysin (ECH) on human monocytes. Nanomolar concentrations of purified ECH (250-2,000 ng/ml) caused rapid and irreversible depletion of cellular ATP to levels below 20% of controls within 60 min....

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Published in:J Clin Invest
Main Authors: Bhakdi, S, Muhly, M, Korom, S, Schmidt, G
Format: Artigo
Language:Inglês
Published: American Society for Clinical Investigation 1990
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC296636/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2189890/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI114631
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