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Human hyperimmune globulin protects against the cytotoxic action of staphylococcal alpha-toxin in vitro and in vivo.
Alpha-toxin, the major cytolysin of Staphylococcus aureus, preferentially attacks human platelets and cultured monocytes, thereby promoting coagulation and the release of interleukin-1 and tumor necrosis factor. Titers of naturally occurring antibodies in human blood are not high enough to substanti...
Gespeichert in:
| Veröffentlicht in: | Infect Immun |
|---|---|
| Hauptverfasser: | , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
American Society for Microbiology (ASM)
1989
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC260792/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2777380/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/iai.57.10.3214-3220.1989 |
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