Low doses of α(2)-adrenoceptor antagonists augment spinal morphine analgesia and inhibit development of acute and chronic tolerance

BACKGROUND AND PURPOSE: Ultra-low doses of opioid receptor antagonists augment spinal morphine antinociception and block the induction of tolerance. Considering the evidence demonstrating functional and physical interactions between the opioid and α(2)-adrenoceptors, this study investigated whether...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Milne, B, Sutak, M, Cahill, C M, Jhamandas, K
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2008
Assuntos:
Research Papers
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2607212/
https://ncbi.nlm.nih.gov/pubmed/18806811
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/bjp.2008.353
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados