Effects of alpha 2-adrenoceptor agonists dexmedetomidine and guanfacine on morphine analgesia and tolerance in rats

BACKGROUND: Alpha 2 (α(2))-adrenoceptor agonists may be useful for their potential to increase or prolong opioid analgesia while attenuating the development of opioid tolerance. The purpose of this study was to investigate the effects of dexmedetomidine and guanfacine (α(2)-adrenoceptor agonists) on...

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Bibliografiske detaljer
Main Authors: Gursoy, Sinan, Ozdemir, Ercan, Bagcivan, Ihsan, Altun, Ahmet, Durmus, Nedim
Format: Artigo
Sprog:Inglês
Udgivet: Informa Healthcare 2011
Fag:
Original Articles
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3207298/
https://ncbi.nlm.nih.gov/pubmed/21919812
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3109/03009734.2011.597889
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