Blockade and reversal of spinal morphine tolerance by peptide and non-peptide calcitonin gene-related peptide receptor antagonists

1. This study examined the effects of the peptide CGRP receptor antagonist CGRP(8-37) and the newly-developed non-peptide CGRP receptor antagonist BIBN4096BS for their potential to both inhibit the development and reverse tolerance to the antinociceptive action of morphine. 2. Repeated administratio...

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Bibliographic Details
Main Authors: Powell, Kelly J, Ma, Weiya, Sutak, Maaja, Doods, Henri, Quirion, Remi, Jhamandas, Khem
Format: Artigo
Language:Inglês
Published: 2000
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Papers
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1572412/
https://ncbi.nlm.nih.gov/pubmed/11053206
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0703655
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