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UBF levels determine the number of active ribosomal RNA genes in mammals
In mammals, the mechanisms regulating the number of active copies of the ∼200 ribosomal RNA (rRNA) genes transcribed by RNA polymerase I are unclear. We demonstrate that depletion of the transcription factor upstream binding factor (UBF) leads to the stable and reversible methylation-independent sil...
Tallennettuna:
| Päätekijät: | , , , , , , , , , , , , , , , |
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| Aineistotyyppi: | Artigo |
| Kieli: | Inglês |
| Julkaistu: |
The Rockefeller University Press
2008
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| Aiheet: | |
| Linkit: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2606969/ https://ncbi.nlm.nih.gov/pubmed/19103806 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200805146 |
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