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Purification of Clostridium difficile toxin A by affinity chromatography on immobilized thyroglobulin.

An efficient, single-step method for isolating highly purified toxin A from Clostridium difficile culture filtrates is described. The purification procedure was based on the affinity binding and release of toxin A to bovine thyroglobulin conjugated to agarose beads. The toxin strongly bound at 4 deg...

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Bibliografiska uppgifter
Huvudupphovsmän: Krivan, H C, Wilkins, T D
Materialtyp: Artigo
Språk:Inglês
Publicerad: 1987
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC260617/
https://ncbi.nlm.nih.gov/pubmed/3112015
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