Hyaluronan Accumulation Is Elevated in Cultures of Low Density Lipoprotein Receptor-deficient Cells and Is Altered by Manipulation of Cell Cholesterol Content

The extracellular matrix molecule hyaluronan (HA) accumulates in human atherosclerotic lesions. Yet the reasons for this accumulation have not been adequately addressed. Because abnormalities in lipid metabolism promote atherosclerosis, we have asked whether disrupted cholesterol homeostasis alters...

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Hlavní autoři: Sakr, Sana W., Potter-Perigo, Susan, Kinsella, Michael G., Johnson, Pamela Y., Braun, Kathleen R., Goueffic, Yann, Rosenfeld, Michael E., Wight, Thomas N.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Biochemistry and Molecular Biology 2008
Témata:
Glycobiology and Extracellular Matrices
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2606012/
https://ncbi.nlm.nih.gov/pubmed/18948257
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M807772200
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