Hyaluronan Accumulation Is Elevated in Cultures of Low Density Lipoprotein Receptor-deficient Cells and Is Altered by Manipulation of Cell Cholesterol Content

The extracellular matrix molecule hyaluronan (HA) accumulates in human atherosclerotic lesions. Yet the reasons for this accumulation have not been adequately addressed. Because abnormalities in lipid metabolism promote atherosclerosis, we have asked whether disrupted cholesterol homeostasis alters...

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Detalhes bibliográficos
Main Authors: Sakr, Sana W., Potter-Perigo, Susan, Kinsella, Michael G., Johnson, Pamela Y., Braun, Kathleen R., Goueffic, Yann, Rosenfeld, Michael E., Wight, Thomas N.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2008
Assuntos:
Glycobiology and Extracellular Matrices
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2606012/
https://ncbi.nlm.nih.gov/pubmed/18948257
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M807772200
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