Hyaluronan Accumulation Is Elevated in Cultures of Low Density Lipoprotein Receptor-deficient Cells and Is Altered by Manipulation of Cell Cholesterol Content

The extracellular matrix molecule hyaluronan (HA) accumulates in human atherosclerotic lesions. Yet the reasons for this accumulation have not been adequately addressed. Because abnormalities in lipid metabolism promote atherosclerosis, we have asked whether disrupted cholesterol homeostasis alters...

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Autors principals: Sakr, Sana W., Potter-Perigo, Susan, Kinsella, Michael G., Johnson, Pamela Y., Braun, Kathleen R., Goueffic, Yann, Rosenfeld, Michael E., Wight, Thomas N.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Biochemistry and Molecular Biology 2008
Matèries:
Glycobiology and Extracellular Matrices
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2606012/
https://ncbi.nlm.nih.gov/pubmed/18948257
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M807772200
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