Caspase 8 Promotes Peripheral Localization and Activation of Rab5

Caspase 8 is a cysteine protease that initiates apoptotic signaling via the extrinsic pathway in a manner dependent upon association with early endosomes. Previously, we identified caspase 8 as an effector of migration, promoting motility in a manner dependent upon phosphorylation on Tyr-380 by Src...

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Hlavní autoři: Torres, Vicente A., Mielgo, Ainhoa, Barilà, Daniela, Anderson, Deborah H., Stupack, Dwayne
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Biochemistry and Molecular Biology 2008
Témata:
Molecular Basis of Cell and Developmental Biology
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2605999/
https://ncbi.nlm.nih.gov/pubmed/18974049
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M805878200
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