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DNA Distortion and Specificity in a Sequence Specific Endonuclease

Five new structures of the Q138F HincII enzyme bound to a total of three different DNA sequences and three different metal ions (Ca(2+), Mg(2+), and Mn(2+)) are presented. While previous structures were produced from soaking Ca(2+) into pre-formed Q138F HincII/DNA crystals, the new structures are de...

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Detalhes bibliográficos
Main Authors: Babic, Andrea C., Little, Elizabeth J., Manohar, Veena M., Bitinaite, Jurate, Horton, Nancy C.
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2605692/
https://ncbi.nlm.nih.gov/pubmed/18762194
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2008.08.032
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