Selective blockade of 2-arachidonoylglycerol hydrolysis produces cannabinoid behavioral effects

2-Arachidonoylglycerol (2-AG) and anandamide are endocannabinoids that activate cannabinoid receptors CB1 and CB2. Endocannabinoid signaling is terminated by enzymatic hydrolysis, a process that, for anandamide, is mediated by fatty acid amide hydrolase (FAAH) and, for 2-AG, is thought to involve mo...

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Bibliografische gegevens
Hoofdauteurs: Long, Jonathan Z., Li, Weiwei, Booker, Lamont, Burston, James J., Kinsey, Steven G., Schlosburg, Joel E., Pavón, Franciso J., Serrano, Antonia M., Selley, Dana E., Parsons, Loren H., Lichtman, Aron H., Cravatt, Benjamin F.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2008
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Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2605181/
https://ncbi.nlm.nih.gov/pubmed/19029917
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nchembio.129
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