Selective blockade of 2-arachidonoylglycerol hydrolysis produces cannabinoid behavioral effects

2-Arachidonoylglycerol (2-AG) and anandamide are endocannabinoids that activate cannabinoid receptors CB1 and CB2. Endocannabinoid signaling is terminated by enzymatic hydrolysis, a process that, for anandamide, is mediated by fatty acid amide hydrolase (FAAH) and, for 2-AG, is thought to involve mo...

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Detalhes bibliográficos
Main Authors: Long, Jonathan Z., Li, Weiwei, Booker, Lamont, Burston, James J., Kinsey, Steven G., Schlosburg, Joel E., Pavón, Franciso J., Serrano, Antonia M., Selley, Dana E., Parsons, Loren H., Lichtman, Aron H., Cravatt, Benjamin F.
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2605181/
https://ncbi.nlm.nih.gov/pubmed/19029917
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nchembio.129
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