The dietary phytochemical indole-3-carbinol is a natural elastase enzymatic inhibitor that disrupts cyclin E protein processing

Indole-3-carbinol (I3C), a naturally occurring component of Brassica vegetables, such as broccoli, cabbage, and Brussels sprouts, induces a G(1) cell-cycle arrest of human breast cancer cells, although the direct cellular targets that mediate this process are unknown. Treatment of highly invasive MD...

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Detalles Bibliográficos
Autores principales: Nguyen, Hanh H., Aronchik, Ida, Brar, Gloria A., Nguyen, David H. H., Bjeldanes, Leonard F., Firestone, Gary L.
Formato: Artigo
Lenguaje:Inglês
Publicado: National Academy of Sciences 2008
Materias:
Biological Sciences
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2604958/
https://ncbi.nlm.nih.gov/pubmed/19064917
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0806581105
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