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Cooperative anti-proliferative signaling by aspirin and indole-3-carbinol targets micropthalmia associated transcription factor gene expression and promoter activity in human melanoma cells

Anti-proliferative signaling of combinations of the nonsteroidal anti-inflammatory drug acetylsalicylic acid (aspirin) and indole-3-carbinol (I3C), a natural indolecarbinol compound derived from cruciferous vegetables, was investigated in human melanoma cells. Melanoma cell lines with distinct mutat...

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Publicado en:Cell Biol Toxicol
Main Authors: Poindexter, Kevin M., Matthew, Susanne, Aronchik, Ida, Firestone, Gary L.
Formato: Artigo
Idioma:Inglês
Publicado: 2016
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4905717/
https://ncbi.nlm.nih.gov/pubmed/27055402
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10565-016-9321-5
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