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Inhibition of Oncogenic BRAF Activity by Indole-3-Carbinol Disrupts Microphthalmia-Associated Transcription Factor Expression and Arrests Melanoma Cell Proliferation

Indole-3-carbinol (I3C), an anti-cancer phytochemical derived from cruciferous vegetables, strongly inhibited proliferation and down-regulated protein levels of the melanocyte master regulator micropthalmia-associated transcription factor (MITF-M) in oncogenic BRAF-V600E expressing melanoma cells in...

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Dades bibliogràfiques
Publicat a:Mol Carcinog
Autors principals: Kundu, Aishwarya, Quirit, Jeanne G., Khouri, Michelle G., Firestone, Gary L.
Format: Artigo
Idioma:Inglês
Publicat: 2016
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4985490/
https://ncbi.nlm.nih.gov/pubmed/26878440
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/mc.22472
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