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Thrombin-mediated increases in cytosolic [Ca(2+)] involve different mechanisms in human pulmonary artery smooth muscle and endothelial cells
Thrombin is a procoagulant inflammatory agonist that can disrupt the endothelium-lumen barrier in the lung by causing contraction of endothelial cells and promote pulmonary cell proliferation. Both contraction and proliferation require increases in cytosolic Ca(2+) concentration ([Ca(2+)](cyt)). In...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Physiological Society
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2604792/ https://ncbi.nlm.nih.gov/pubmed/18836030 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajplung.90259.2008 |
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