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Chronic exposure to fibrin and fibrinogen differentially regulates intracellular Ca(2+) in human pulmonary arterial smooth muscle and endothelial cells

Acute pulmonary embolism occurs in more than half a million people a year in the United States. Chronic thromboembolic pulmonary hypertension (CTEPH) develops in ∼4% of these patients due to unresolved thromboemboli. CTEPH is thus a relatively common, progressive, and potentially fatal disease. One...

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Main Authors: Firth, Amy L., Yau, Jocelyn, White, Amanda, Chiles, Peter G., Marsh, James J., Morris, Timothy A., Yuan, Jason X.-J.
Formato: Artigo
Idioma:Inglês
Publicado: American Physiological Society 2009
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2692802/
https://ncbi.nlm.nih.gov/pubmed/19363122
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajplung.90412.2008
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