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Substitution of Brown Norway chromosome 16 preserves cardiac function with aging in a salt-sensitive Dahl consomic rat

Determination of the genetic factors that control the progression of left ventricular hypertrophy (LVH) to heart failure has been difficult despite extensive study in animal models. Here we have characterized a consomic rat model of LVH resulting from the introgression of chromosome 16 from the norm...

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Main Authors: Kriegel, A. J., Greene, A. S.
Formato: Artigo
Idioma:Inglês
Publicado: American Physiological Society 2008
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2604784/
https://ncbi.nlm.nih.gov/pubmed/18940898
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/physiolgenomics.00054.2008
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