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Chromosome substitution reveals the genetic basis of Dahl salt-sensitive hypertension and renal disease

This study examined the genetic basis of hypertension and renal disease in Dahl SS/Mcwi (Dahl Salt-Sensitive) rats using a complete chromosome substitution panel of consomic rats in which each of the 20 autosomes and the X and Y chromosomes were individually transferred from the Brown Norway (BN) ra...

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Detalhes bibliográficos
Main Authors: Mattson, David L., Dwinell, Melinda R., Greene, Andrew S., Kwitek, Anne E., Roman, Richard J., Jacob, Howard J., Cowley, Allen W.
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2536867/
https://ncbi.nlm.nih.gov/pubmed/18653478
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajprenal.90341.2008
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