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Mechanism of Differential Cardiovascular Response to Propofol in Dahl Salt-Sensitive, Brown Norway, and Chromosome 13-Substituted Consomic Rat Strains: Role of Large Conductance Ca(2+) and Voltage-Activated Potassium Channels

Cardiovascular sensitivity to general anesthetics is highly variable among individuals in both human and animal models, but little is known about the genetic determinants of drug response to anesthetics. Recently, we reported that propofol (2,6-diisopropylphenol) causes circulatory instability in Da...

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Detaylı Bibliyografya
Asıl Yazarlar: Stadnicka, Anna, Contney, Stephen J., Moreno, Carol, Weihrauch, Dorothee, Bosnjak, Zeljko J., Roman, Richard J., Stekiel, Thomas A.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Society for Pharmacology and Experimental Therapeutics 2009
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC2729794/
https://ncbi.nlm.nih.gov/pubmed/19541907
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/jpet.109.154104
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