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Rationalizing translation attenuation in the network architecture of the unfolded protein response
Increased levels of unfolded proteins in the endoplasmic reticulum (ER) of all eukaryotes trigger the unfolded protein response (UPR). Lower eukaryotes solely use an ancient UPR mechanism, whereby they up-regulate ER-resident chaperones and other enzymatic activities to augment protein folding and e...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2603256/ https://ncbi.nlm.nih.gov/pubmed/19075238 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0803476105 |
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