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Sensitivity of breast cancer cells to erlotinib depends on cyclin-dependent kinase 2 activity
Inhibitors of epidermal growth factor receptor (EGFR) tyrosine kinases,such as erlotinib and gefitinib, have not been very effective in the treatment of breast cancer although many breast cancer cells express EGFR. To address this apparent paradox, we examined possible predictors of the sensitivity...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2007
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2603172/ https://ncbi.nlm.nih.gov/pubmed/17671085 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1535-7163.MCT-06-0514 |
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