Nalaganje...
S6K Directly Phosphorylates IRS-1 on Ser-270 to Promote Insulin Resistance in Response to TNF-α Signaling through IKK2
S6K1 (p70S6K) is a serine kinase downstream from Akt in the insulin signaling pathway that is involved in negative feedback regulation of insulin action. S6K1 is also activated by TNF-α, a pro-inflammatory cytokine. However, its role remains to be characterized. In the current study, we elucidated a...
Shranjeno v:
| Main Authors: | , , , , |
|---|---|
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
American Society for Biochemistry and Molecular Biology
2008
|
| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2602883/ https://ncbi.nlm.nih.gov/pubmed/18952604 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M806480200 |
| Oznake: |
Označite
Brez oznak, prvi označite!
|