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The Interrelationship of Helicase and Nuclease Domains during DNA Translocation by the Molecular Motor EcoR124I

The type I restriction–modification enzyme EcoR124I comprises three subunits with the stoichiometry HsdR(2)/HsdM(2)/HsdS(1). The HsdR subunits are archetypical examples of the fusion between nuclease and helicase domains into a single polypeptide, a linkage that is found in a great many other DNA pr...

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Main Authors: Šišáková, Eva, Weiserová, Marie, Dekker, Cees, Seidel, Ralf, Szczelkun, Mark D.
格式: Artigo
語言:Inglês
出版: Elsevier 2008
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC2602864/
https://ncbi.nlm.nih.gov/pubmed/18952104
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2008.10.017
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