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When a helicase is not a helicase: dsDNA tracking by the motor protein EcoR124I
Using a combination of single molecule and bulk solution measurements, we have examined the DNA translocation activity of a helicase, the Type I restriction modification enzyme EcoR124I. We find that EcoR124I can translocate past covalent interstrand crosslinks, inconsistent with an obligatory unwin...
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| Hlavní autoři: | , , , , , |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
2006
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1462981/ https://ncbi.nlm.nih.gov/pubmed/16642041 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.emboj.7601104 |
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